NDLI: HLA Dr Antigens in Rheumatoid Arthritis

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HLA Dr Antigens in Rheumatoid Arthritis

Content Provider	Scilit
Author	Gran, Jan Tore Husby, Gunnar Thorsby, Erik
Copyright Year	1983
Description	Journal: Scandinavian Journal of Rheumatology The prevalence and possible prognostic significance of HLA-DR antigens have been studied in 129 patients with seropositive (RF-positive) classical rheumatoid arthritis (RA). HLA-DR4 was increased in RA, whilst HLA-DR2 was decreased, though it was not associated with either low titres of RF or with good prognosis. HLA-DR3-positive patients had the highest prevalence of antibodies to nuclear antigens, and the antigen correlated negatively to the presence of subcutaneous nodules, bony erosions and familial RA. RA patients possessing DR3 thus had some of the characteristics of SLE. HLA-DR5 was not present in male RA patients. An absence of familial RA was observed among DRw8-positive patients.
Related Links	http://www.tandfonline.com/doi/pdf/10.3109/03009748309098541
Ending Page	245
Page Count	5
Starting Page	241
ISSN	03009742
e-ISSN	15027732
DOI	10.3109/03009748309098541
Journal	Scandinavian Journal of Rheumatology
Issue Number	3
Volume Number	12
Language	English
Publisher	Informa UK Limited
Publisher Date	1983-01-01
Access Restriction	Open
Subject Keyword	Journal: Scandinavian Journal of Rheumatology Rheumatoid Arthritis Hla Dr Antigens Antigens in Rheumatoid
Content Type	Text
Subject	Immunology and Allergy Immunology Rheumatology

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