NDLI: In Vitro Studies in Reproductive Immunology, 3. Restoration of Mitogenic Activity of Lymphocytes Inhibited by Seminal Plasma in Man

Content Provider	Scilit
Author	Marcus, Z. H. Hess, E. V.
Copyright Year	1981
Description	Journal: Archives of andrology Human seminal plasma, (HuSePl) is inhibitory to mitogen (PHA-M, Con-A, and PWM) lymphocyte activation. The inhibition does not require the continuous presence of HuSePl. Lymphocyte cultures remain inhibited after 24-hr contact with HuSePl and subsequent washings. Addition of fresh autochthonous lymphocytes or T cells but not B cells can restore the mitogenic activity of HuSePl-inhibited lymphocyte cultures. These observations suggest that T-lymphocyte in the male genital tract are surveilled by HuSePl and lack of inhibitory material could induce an immunologic response by spermatozoal antigens.
Related Links	http://www.tandfonline.com/doi/pdf/10.3109/01485018108987348
Ending Page	74
Page Count	8
Starting Page	67
ISSN	01485016
e-ISSN	15210375
DOI	10.3109/01485018108987348
Journal	Archives of andrology
Issue Number	1
Volume Number	6
Language	English
Publisher	Informa UK Limited
Publisher Date	1981-01-01
Access Restriction	Open
Subject Keyword	Journal: Archives of andrology Endocrinology and Metabolism Reproductive Biology Spermatozoal
Content Type	Text
Subject	Endocrinology

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In Vitro Studies in Reproductive Immunology, 3. Restoration of Mitogenic Activity of Lymphocytes Inhibited by Seminal Plasma in Man