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Valvular calcification and left ventricular modifying in peritoneal dialysis patients
| Content Provider | Scilit |
|---|---|
| Author | Rebić, Damir Rašić, Senija Hamzić-Mehmedbašić, Aida Džemidžić, Jasminka Kurtalić, Emir |
| Copyright Year | 2015 |
| Description | Journal: Renal Failure Background: Cardiac valve calcification (CVC) and left ventricular (LV) alterations are frequent complication in end-stage renal disease (ESRD). We determined the prevalence of CVC and LV hypertrophy (LVH) in ESRD patients before renal replacement therapy and 12 months after peritoneal dialysis (PD). Methods: A prospective longitudinal of 50 incident PD patients was studied. Demographic and clinical data were recorded and blood assayed at baseline and after 1-year of follow-up. CVC and LVH were evaluated by M-mode two-dimensional echocardiography. Results: CVC of the mitral and aortic valves and of both valves were noted in 30, 18 and 10% of patients, respectively. After 12 months of PD regimen, 20% patients had aortic, 24% mitral and 8% had calcification of both valves. After one year of PD, LVH was 62 and 36% in patients with and without CVC, respectively (p < 0.05). Endothelin-1 is an independent predictor of CVC at the baseline, while nitric oxide is inversely an independent predictor at the end of follow-up. Conclusions: CVC is associated with LVH in PD patients. These findings identified a potential role for monitored markers to be incorporated into therapeutic strategies aimed at detection and treatment of cardiovascular complications and prevention strategies. |
| Related Links | https://www.tandfonline.com/doi/pdf/10.3109/0886022X.2015.1073495?needAccess=true https://www.tandfonline.com/doi/pdf/10.3109/0886022X.2015.1073495 |
| Ending Page | 1322 |
| Page Count | 7 |
| Starting Page | 1316 |
| ISSN | 0886022X |
| e-ISSN | 15256049 |
| DOI | 10.3109/0886022x.2015.1073495 |
| Journal | Renal Failure |
| Issue Number | 8 |
| Volume Number | 37 |
| Language | English |
| Publisher | Informa UK Limited |
| Publisher Date | 2015-08-14 |
| Access Restriction | Open |
| Subject Keyword | Journal: Renal Failure Medical Laboratory Technology Cardiac Valve Calcification End-stage Renal Disease Left Ventricular Alterations Peritoneal Dialysis |
| Content Type | Text |
| Subject | Critical Care and Intensive Care Medicine Nephrology |
