NDLI: Microneedles: Current Trends and Applications

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Microneedles: Current Trends and Applications

Content Provider	Scilit
Author	Manoj, Hima Gupta, Pallavi Mohan, Loganathan Nagai, Moeto Wankhar, Syrpailyne Santra, Tuhin S.
Copyright Year	2020
Description	The shortcomings of oral drug delivery and the pain associated with hypodermic needles have shifted the drug delivery orientation toward the transdermal route. This chapter focuses on the history, types, mechanisms, and applications of drug delivery, along with the recent innovations in microneedle drug delivery systems. It highlights the delivery of different therapeutic agents efficiently via microneedles of various designs and compositions, ultimately showing the potential role of microneedles as a transdermal drug delivery system. There are two major factors determining the mechanism of delivery via microneedles: mechanical disruption of the skin and release of the drug or vaccine within the epidermis layer. Microneedles need to be stored under conditions that maintain drug activity and ensure microneedle integrity, like sharpness, strength, and sterility. Microneedles can be used for needle-free delivery of anesthetics. As they are minimally invasive in nature, cause no pain, and are small in size (100 microns), they play a major role in drug delivery. Book Name: Microfluidics and Bio-MEMS
Related Links	https://content.taylorfrancis.com/books/download?dac=C2019-0-09459-5&isbn=9781003014935&doi=10.1201/9781003014935-7&format=pdf
Ending Page	342
Page Count	68
Starting Page	275
DOI	10.1201/9781003014935-7
Language	English
Publisher	Informa UK Limited
Publisher Date	2020-08-31
Access Restriction	Open
Subject Keyword	Book Name: Microfluidics and Bio-mems Biomedical Engineering Vaccine Microneedles Transdermal Drug Delivery Systems
Content Type	Text
Resource Type	Chapter

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