NDLI: The Characterization of Polyanhydride Microspheres

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The Characterization of Polyanhydride Microspheres

Content Provider	Scilit
Author	Brunner, Anette Göpferich, Achim
Copyright Year	2020
Description	This chapter discusses the properties of polyanhydrides before and during erosion and shows physicochemical ways of polyanhydride microsphere characterization. To understand the characteristics of polyanhydride microspheres, it is necessary to have a detailed knowledge of the properties of the polymers. Polyanhydrides have been investigated thoroughly during the last couple of years, which makes much physicochemical data available. Polyanhydrides are partially crystalline and, therefore, have a typical appearance under polarized light. The crystallinity of polyanhydrides can be adjusted through the copolymer composition. Important parameters for processing polyanhydrides to dosage forms are the glass transition temperature and the melting point. An understanding of polyanhydride erosion and degradation is essential to understand the properties of eroding polyanhydride microspheres. The techniques used for the characterization of polymer bulk erosion are also suited for the investigation of microspheres. An interesting approach to the reduction of organic solvent residues in polyanhydride microspheres is the formation of microspheres from melted polymer. Book Name: Microparticulate Systems for the Delivery of Proteins and Vaccines
Related Links	https://content.taylorfrancis.com/books/download?dac=C2010-0-29490-7&isbn=9781003067542&doi=10.1201/9781003067542-6&format=pdf
Ending Page	202
Page Count	34
Starting Page	169
DOI	10.1201/9781003067542-6
Language	English
Publisher	Informa UK Limited
Publisher Date	2020-07-24
Access Restriction	Open
Subject Keyword	Book Name: Microparticulate Systems for the Delivery of Proteins and Vaccines Polymer Science Erosion Polyanhydride Microspheres Crystalline Physicochemical Melting Polymer Characterization Properties
Content Type	Text
Resource Type	Chapter

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