Neurobehavioral alterations in an adolescent following posterior fossa tumor resection

Content Provider	Scilit
Author	Baillieux, Hanne Smet, Hyo Jung De Lesage, Geoffrey Paquier, Philippe Deyn, Peter P. De Mariën, Peter
Copyright Year	2006
Description	The posterior fossa syndrome (PFS) consists of a variety of symptoms, including cerebellar mutism, behavioral disturbances and personality changes. We report longitudinal clinical, neuroradiological and neurobehavioral findings in a 19-year-old left-handed patient, diagnosed with attentional deficit hyperactivity disorder (ADHD) at the age of 12, who underwent posterior fossa tumor resection. Although the patient did not develop cerebellar mutism after surgery, marked apathy and emotional indifference, urinary retention, eye-lid apraxia and visual hallucinosis became apparent after a brief interval of normal functioning. Based on these findings it is argued that the PFS might be considered a semiological heterogeneous condition with variable clinical expressions. Long-term follow-up investigations revealed subtle, but significant cognitive and affective deficits, resembling the cerebellar cognitive affective syndrome in adults. As demonstrated by functional neuroimaging studies with SPECT, symptoms were associated with perfusional deficits in the anatomoclinically suspected supratentorial regions, reflecting the distant impact of the cerebellum on cognitive and affective functions.
Related Links	https://link.springer.com/content/pdf/10.1080/14734220601009606.pdf
Ending Page	295
Page Count	7
Starting Page	289
ISSN	14734222
e-ISSN	14734230
DOI	10.1080/14734220601009606
Journal	The Cerebellum
Issue Number	4
Volume Number	5
Language	English
Publisher	Informa UK Limited
Publisher Date	2006-12-01
Access Restriction	Open
Subject Keyword	Neuroimaging Functional Neuroimaging
Content Type	Text
Resource Type	Article
Subject	Neurology Neurology (clinical)