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Age‐related macular degeneration—emerging pathogenetic and therapeutic concepts
| Content Provider | Scilit |
|---|---|
| Author | Gehrs, Karen Anderson, Don H. Johnson, Lincoln V. Hageman, Gregory S. |
| Copyright Year | 2006 |
| Description | Today, the average life expectancy in developed nations is over 80 years and climbing. And yet, the quality of life during those additional years is often significantly diminished by the effects of age-related, degenerative diseases, including age-related macular degeneration (AMD), the leading cause of blindness in the elderly worldwide. AMD is characterized by a progressive loss of central vision attributable to degenerative and neovascular changes in the macula, a highly specialized region of the ocular retina responsible for fine visual acuity. Estimates gathered from the most recent World Health Organization (WHO) global eye disease survey conservatively indicate that 14 million persons are blind or severely visually impaired because of AMD. The disease has a tremendous impact on the physical and mental health of the geriatric population and their families and is becoming a major public health burden. |
| Related Links | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4853957/pdf |
| Ending Page | 471 |
| Page Count | 22 |
| Starting Page | 450 |
| ISSN | 07853890 |
| e-ISSN | 13652060 |
| DOI | 10.1080/07853890600946724 |
| Journal | Annals of Medicine |
| Issue Number | 7 |
| Volume Number | 38 |
| Language | English |
| Publisher | Informa UK Limited |
| Publisher Date | 2006-01-01 |
| Access Restriction | Open |
| Subject Keyword | Age-related Macular Degeneration (amd) Basal Laminar Deposit (blamd) Bruch's Membrane Choroidal Neovascularization Complement Factor B (bf) Complement Factor H (cfh) Drusen Epidemiology Genetics Geographic Atrophy Inflammation Surgery |
| Content Type | Text |
| Resource Type | Article |
| Subject | Medicine |
