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Comparative diagnostic accuracy of ACE-III and MoCA for detecting mild cognitive impairment
| Content Provider | Scilit |
|---|---|
| Author | Wang, Bian-Rong Zheng, Hui-Fen Xu, Chang Sun, Yi Zhang, Ying-Dong Shi, Jian-Quan |
| Copyright Year | 2019 |
| Description | Objective: The aim of this study was to validate the reliability of the Chinese version of Addenbrooke's Cognitive Examination III (ACE-III) for detecting mild cognitive impairment. Furthermore, the present study compares the diagnostic accuracy of ACE-III with that of Montreal Cognitive Assessment (MoCA). Methods: One hundred and twenty patients with MCI and 136 healthy controls were included in the study. All patients were evaluated by the Chinese version of ACE-III, MoCA and MMSE. Results: Subjects in the control group showed better performance in ACE-III total score and its subdomain scores than those in the MCI group. There was a significantly positive correlation between ACE-III total score and MoCA score. Meanwhile, there was also a significantly positive correlation between ACE-III total score and MMSE score. For ACE-III total score, a cut-off point of 85 yielded a sensitivity of 97.3% and a specificity of 90.7%. The AUC for ACE-III total score was 0.978. For MoCA, a cut-off point of 23 yielded a sensitivity of 86.5% and a specificity of 97.7%. The AUC for MoCA was 0.961. There were no significant differences in diagnostic accuracy between ACE-III and MoCA. Conclusion: The present findings support that both ACE-III and MoCA are useful for detecting MCI in early stages. |
| Related Links | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6750842/pdf https://www.dovepress.com/getfile.php?fileID=52744 |
| Ending Page | 2653 |
| Page Count | 7 |
| Starting Page | 2647 |
| ISSN | 11766328 |
| e-ISSN | 11782021 |
| DOI | 10.2147/ndt.s212328 |
| Journal | Neuropsychiatric disease and treatment |
| Volume Number | 15 |
| Language | English |
| Publisher | Informa UK Limited |
| Publisher Date | 2019-09-01 |
| Access Restriction | Open |
| Subject Keyword | Rehabilitation Addenbrooke's Cognitive Examination Iii Montreal Cognitive Assessment Cognitive Screening Mild Cognitive Impairment |
| Content Type | Text |
| Resource Type | Article |
