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Retinal Microvasculature Changes After Repair of Macula-off Retinal Detachment Assessed with Optical Coherence Tomography Angiography
| Content Provider | Scilit |
|---|---|
| Author | McKay, K. Matthew Vingopoulos, Filippos Wang, Jay C. Papakostas, Thanos D. Silverman, Rebecca F. Marmalidou, Anna Lains, Inês Eliott, Dean Vavvas, Demetrios G. Kim, Leo A. Wu, David M. Miller, John B. |
| Copyright Year | 2020 |
| Description | Objective: To characterize the microvascular retinal changes after repair of macula-off rhegmatogenous retinal detachment (RRD) using optical coherence tomography angiography (OCT-A). Patients and Methods: A retrospective review of patients who underwent repair of macula-off RRD. Fellow unaffected eyes were used as controls. Post-operative OCT-A allowed comparison of vessel density (VD) and foveal avascular zone (FAZ) area in the superficial and deep retinal capillary plexus (DCP) as well as VD in the choriocapillaris layer. Results: Seventeen eyes of 17 RRD patients were included in the final analysis. There was a reduction in VD of the deep retinal capillary plexus in affected eyes compared to fellow eyes (p = 0.046). RRD eyes with reduced VD in DCP compared with their fellow control eyes had worse visual acuity after repair compared to those without (p = 0.032). No significant microvasculature changes were detected in the FAZ area and VD in the superficial capillary plexus and choriocapillaris compared to fellow eyes. Conclusion: In macula-off RRD eyes, significant microvascular changes were detected in the DCP using OCT-A even after successful anatomical repair. Decreased VD in the DCP compared to the fellow healthy eyes was correlated with worse visual acuity. |
| Related Links | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7326212/pdf https://www.dovepress.com/getfile.php?fileID=59208 |
| Ending Page | 1767 |
| Page Count | 9 |
| Starting Page | 1759 |
| ISSN | 11775467 |
| e-ISSN | 11775483 |
| DOI | 10.2147/opth.s214623 |
| Journal | Clinical Ophthalmology |
| Volume Number | 14 |
| Language | English |
| Publisher | Informa UK Limited |
| Publisher Date | 2020-06-01 |
| Access Restriction | Open |
| Subject Keyword | Ophthalmology Oct-angiography Macula-off Retinal Detachment Microvascular Changes |
| Content Type | Text |
| Resource Type | Article |
| Subject | Ophthalmology |
