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Deposition and Passage of Transthyretin Through the Blood-Nerve Barrier in Recipients of Familial Amyloid Polyneuropathy Livers
| Content Provider | Scilit |
|---|---|
| Author | Sousa, M. M. Ferrão, J. Fernandes, R. Guimarães, A. Geraldes, J. B. Perdigoto, R. Tomé, L. Mota, O. Negrão, L. Furtado, A. L. Saraiva, M. J. |
| Copyright Year | 2004 |
| Description | Given the fact that approximately 90% of plasma transthyretin (TTR) is produced by the liver, liver transplantation (LT) has been used to abolish the production of most of the mutant TTR in familial amyloid polyneuropathy (FAP). As the shortage of donor livers has been the rate-limiting factor in the expansion of LT, domino liver transplantation (DLT), has been performed; in this procedure FAP patients receive and sequentially donate grafts to other recipients. However DLT involves specific ethical problems namely, the graft of a liver producing a pathogenic protein. Book Name: Amyloid and Amyloidosis |
| Related Links | https://content.taylorfrancis.com/books/download?dac=C2010-0-33252-7&isbn=9780429125249&doi=10.1201/9781420037494-126&format=pdf |
| Ending Page | 359 |
| Page Count | 3 |
| Starting Page | 357 |
| DOI | 10.1201/9781420037494-126 |
| Language | English |
| Publisher | Informa UK Limited |
| Publisher Date | 2004-11-29 |
| Access Restriction | Open |
| Subject Keyword | Book Name: Amyloid and Amyloidosis Transplantation Protein Liver Transplantation Amyloid Shortage Passage Transthyretin Recipients Donate |
| Content Type | Text |
| Resource Type | Chapter |