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Synthesis ofN-[2-O-(2-Acetamido-1,5-anhydro-2,3-dideoxy-D-glucitol-3-yl)-d-lactoyl]-l-alanyl-d-isoglutamine (1-Deoxy-MDP) and Some of Its Lipophilic Analogs, and Their Immunoadjuvant Activities
| Content Provider | Scilit |
|---|---|
| Author | Hasegawa, Akira Hioki, Yuichi Seki, Eiji Kiso, Makoto Azuma, Ichiro |
| Copyright Year | 1986 |
| Description | N-[2-O-(2-Acetamido-1,5-anhydro-2,3-dideoxy-d-glucitol-3-yl)-d-lactoyl]-l-alanyl-d-isoglutamine (1-deoxy-MDP) and its lipophilic analogs were synthesized from 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-α-d-glucopyranosyl chloride. The immunoadjuvant activity was examined in order to clarify the structural requirements of the carbohydrate moiety and the effects of the lipophilic character for this activity in N-acetylmuramoyl-l-alanyl-d-isoglutamine (MDP). |
| Related Links | https://www.tandfonline.com/doi/pdf/10.1080/00021369.1986.10867643?needAccess=true |
| Ending Page | 1878 |
| Page Count | 6 |
| Starting Page | 1873 |
| ISSN | 09168451 |
| e-ISSN | 13476947 |
| DOI | 10.1080/00021369.1986.10867643 |
| Journal | Bioscience, Biotechnology, and Biochemistry |
| Issue Number | 7 |
| Volume Number | 50 |
| Language | English |
| Publisher | Informa UK Limited |
| Publisher Date | 1986-07-01 |
| Access Restriction | Open |
| Subject Keyword | Medicinal Chemistry Organic Chemistry Lipophilic Structural Acetamido Anhydro Alanyl Dideoxy Glucitol Lactoyl Deoxy Mdp |
| Content Type | Text |
| Resource Type | Article |
| Subject | Organic Chemistry Medicine Analytical Chemistry Molecular Biology Biochemistry Applied Microbiology and Biotechnology Biotechnology |
