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Roles of High-Performance Liquid Chromatography in Nuclear Medicine
| Content Provider | Scilit |
|---|---|
| Author | Wong, Steven How-Yan |
| Copyright Year | 2021 |
| Description | Nuclear medicine is devoted mainly to diagnosis by administering radiopharmaceuticals to patients, followed by imaging the organs or regions of interest. Thus, chromatography has played an intimate role in nuclear medicine research and development. The roles of High-Performance Liquid Chromatography (HPLC) in nuclear medicine are discussed in terms of preparation, purification, and quality control of radiopharmaceuticals and labeled compounds. Radiopharmaceuticals are radioactive "drugs" used primarily for diagnosis in nuclear medicine. These drugs are administered to patients at dose levels that do not result in significant radiation exposure and pharmacological effect. The continued growth of nuclear medicine creates a need for new radiopharmaceuticals; HPLC will be a useful tool in the research and development of these new drugs. The primary roles of HPLC as a supporting instrument include the analysis, purification, and quality control of radiolabeled compounds and radiopharmaceuticals. As the growth of nuclear medicine continues, HPLC will offer considerable help in radiopharmaceutical research and development. Book Name: Advances in Chromatography |
| Related Links | https://api.taylorfrancis.com/content/chapters/edit/download?identifierName=doi&identifierValue=10.1201/9781003209690-1&type=chapterpdf |
| DOI | 10.1201/9781003209690-1 |
| Language | English |
| Publisher | Informa UK Limited |
| Publisher Date | 2021-07-26 |
| Access Restriction | Open |
| Subject Keyword | Book Name: Advances in Chromatography Nuclear Medicine Radiopharmaceuticals Purification Compounds Quality Liquid Chromatography |
| Content Type | Text |
| Resource Type | Chapter |