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Pulsed Nano-Electrospray Ionization: Characterization of Temporal Response and Implementation with a Flared Inlet Capillary
| Content Provider | Scilit |
|---|---|
| Author | Bushey, Jared M. Kaplan, Desmond A. Danell, Ryan M. Glish, Gary L. |
| Copyright Year | 2009 |
| Description | The temporal response of pulsed nano-electrospray ionization mass spectrometry (nano-ESI-MS) was studied and its influence on ion formation and detection was characterized. Rise and decay times for the mass resolved ion current were determined to be 20 ± 3 msec and 61 ± 5 msec, respectively, which led to a maximum pulse rate of 12 Hz. Pulsed nano-ESI operation was demonstrated from a multi-sprayer source controlled by a high voltage pulsing circuit constructed in-house. The desired source mode of operation (e.g. pulsing or continuous) can be realized solely by controlling the voltage applied to each sprayer. |
| Related Links | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3141176/pdf |
| Ending Page | 273 |
| Page Count | 17 |
| Starting Page | 257 |
| ISSN | 10739149 |
| e-ISSN | 15256030 |
| DOI | 10.1080/10739140902831313 |
| Journal | Instrumentation Science & Technology |
| Issue Number | 3 |
| Volume Number | 37 |
| Language | English |
| Publisher | Informa UK Limited |
| Publisher Date | 2009-04-15 |
| Access Restriction | Open |
| Subject Keyword | Analytical Chemistry Coatings and Films Mass Spectrometry Nano-esi Pulsed Esi Esi Temporal Response Flared Inlet Capillary Dual Ion Source |
| Content Type | Text |
| Resource Type | Article |
| Subject | Instrumentation Chemical Engineering Environmental Science |