Cerebellar ataxia associated with anti-glutamic acid decarboxylase autoantibodies

Content Provider	Scilit
Author	Vianello, M. Tavolato, B. Armani, M. Giometto, Bruno
Copyright Year	2003
Description	Recent reports describe the detection of high titres of antibodies to glutamic acid decarboxylase (GAD-Ab) in the serum and cerebrospinal fluid (CSF) of patients with cerebellar ataxia. Most of these cases are females with Polyglandular Autoimmune Disorder who develop a chronic cerebellar syndrome. The CSF profile is in keeping with an autoimmune disorder and intrathecal GAD-Ab synthesis has been demonstrated. The ataxia could reverse after immunomodulatory treatments suggesting a possible pathogenetic role for GAD-Ab.
Related Links	https://link.springer.com/content/pdf/10.1080/14734220309432.pdf
Ending Page	79
Page Count	3
Starting Page	77
ISSN	14734222
e-ISSN	14734230
DOI	10.1080/14734220309432
Journal	The Cerebellum
Issue Number	1
Volume Number	2
Language	English
Publisher	Informa UK Limited
Publisher Date	2003-01-01
Access Restriction	Open
Subject Keyword	Medical Laboratory Technology Antibodies Intrathecal Treatments Autoimmune Ataxia Cerebellar Decarboxylase Glutamic Polyglandular
Content Type	Text
Resource Type	Article
Subject	Neurology Neurology (clinical)