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Peripheral Nerve Regeneration in Gore-Tex Chambers
| Content Provider | Scilit |
|---|---|
| Author | Danielsen, Nils Williams, Lawrence R. Dahlin, Lars B. Varon, Silvio Lundborg, Göran |
| Copyright Year | 1988 |
| Description | Gore-tex chambers were used to bridge a 6 mm gap between the proximal and distal nerve stumps of a rat sciatic nerve. The wall structure of these chambers is characterized by “nodes” interconnected by smaller fibrils. Chambers with internodal distances of 5, 10 and 30 μm were used. Some 30 μm chambers were coated from the outside with Gore-tex (0.2 μm internodal distance) and others were coated from the inside. Regeneration after 12 weeks, as evidenced by muscle action potential recordings and light microscopy, was successful regardless of what type of chamber had been used. The organization of the nerve structure varied among different chamber types. A well organized coaxial nerve structure with myelinated axons was observed if inner-coated chambers were used. In chambers that were not coated or in outer-coated chambers tissue completely filled the chambers, and myelinated axons were arranged in mini-fascicles surrounded by loose connective tissue. |
| Related Links | http://www.tandfonline.com/doi/pdf/10.3109/02844318809097945 |
| Ending Page | 210 |
| Page Count | 4 |
| Starting Page | 207 |
| ISSN | 00365556 |
| DOI | 10.3109/02844318809097945 |
| Journal | Scandinavian journal of plastic and reconstructive surgery |
| Issue Number | 3 |
| Volume Number | 22 |
| Language | English |
| Publisher | Informa UK Limited |
| Publisher Date | 1988-01-01 |
| Access Restriction | Open |
| Subject Keyword | Anatomy Peripheral Nerve Nerve Regeneration Gore Tex Tex Chambers Regeneration in Gore |
| Content Type | Text |
| Resource Type | Article |
| Subject | Surgery |