Loading...
Please wait, while we are loading the content...
Similar Documents
Type 2 Diabetic Patients with Nephropathy in a Scandinavian Kidney-Transplant Population
| Content Provider | Scilit |
|---|---|
| Author | Nyberg, G. Hartsö, M. Mjörnstedt, L. Nordén, G. |
| Copyright Year | 1996 |
| Description | Twenty-seven patients in a cohort of 1000 who received kidney transplants in Göteborg 1985-1993 were found to have diabetes of Type 2 as primary cause of renal failure. All took insulin at the time of transplantation. Four received concomitant pancreas transplants. Mean age was 53 years (range 40-64). All but four were men. Average waiting time on dialysis was less than a year. One year after transplantation 24 of 27 (89%) were alive, 22 (81%) with functioning grafts. However, during follow-up for a total of 51 +/- 27 months 9 (33%) of the diabetic patients died, mainly of cardiac disease or sudden death (n = 7), compared with 17% of matched controls (NS). Diabetic patients had an increased risk of death with a functioning graft, 6/27 versus 3/54 controls (p = 0.02). Graft survival rates were 56% and 65%, respectively (NS). Morbidity was dominated by cardiovascular events and foot ulcers leading to amputations (six patients) and septicaemia. During follow-up body mass index increased from 24.6 +/- 3.0 to 25.9 +/- 3.4 kg/m2. There was no difference in HbA1c-values although one pancreas-transplanted patient remained insulin-independent. The mortality and morbidity rates in this positive selection from a much larger population of Type 2 diabetic patients supports continued restriction in the acceptance rate for transplantation. Type 2 diabetes is not an indication for pancreas transplantation, which is one reason to distinguish this form of diabetes. |
| Related Links | http://www.tandfonline.com/doi/pdf/10.3109/00365599609182314 |
| Ending Page | 322 |
| Page Count | 6 |
| Starting Page | 317 |
| ISSN | 00365599 |
| e-ISSN | 16512065 |
| DOI | 10.3109/00365599609182314 |
| Journal | Scandinavian journal of urology and nephrology |
| Issue Number | 4 |
| Volume Number | 30 |
| Language | English |
| Publisher | Informa UK Limited |
| Publisher Date | 1996-08-01 |
| Access Restriction | Open |
| Subject Keyword | Journal: Scandinavian Journal of Urology and Nephrology Transplantation Insulin Diabetes Functioning Diabetic Patients Death Survival Morbidity Graft |
| Content Type | Text |
| Resource Type | Article |
| Subject | Urology Nephrology |
