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A SINGLE INSTITUTIONAL EXPERIENCE: Is Epoetin Alpha Effective in Anemic Children with Cancer?
| Content Provider | Scilit |
|---|---|
| Author | Yilmaz, D. Cetingul, N. Kantar, M. Öniz, H. Kansoy, S. Kavakli, K. |
| Copyright Year | 2004 |
| Description | The authors aimed to investigate the efficacy of epoetin-alpha on hemoglobin levels and red cell transfusion requirement in children with both hematologic malignancy (HM, n = 27) and solid tumors (ST, n = 14). Epoetin-alpha was given (150 U/kg or 250 U/kg, thrice weekly) for 12 weeks. Epoetin alpha significantly increased the hemoglobin levels at the 2nd and 3rd months of therapy (p <.05). At the 3rd month, the patients required less red cell transfusion. At the dose of 150 U/kg, only three patients with HM, but none of the ST patients, required red cell. However, none required red cell transfusion after 2nd month on epoetin alpha 250 U/kg. Epoetin-alpha administration increases hemoglobin levels and decreases red cell transfusion requirement in children with malignancy. |
| Related Links | http://www.tandfonline.com/doi/pdf/10.1080/08880010490263281?needAccess=true |
| Ending Page | 8 |
| Page Count | 8 |
| Starting Page | 1 |
| ISSN | 08880018 |
| e-ISSN | 15210669 |
| DOI | 10.1080/08880010490263281 |
| Journal | Pediatric hematology and oncology |
| Issue Number | 1 |
| Volume Number | 21 |
| Language | English |
| Publisher | Informa UK Limited |
| Publisher Date | 2004-01-01 |
| Access Restriction | Open |
| Subject Keyword | Journal: Pediatric Hematology and Oncology Pediatrics and Child Health Cancer |
| Content Type | Text |
| Resource Type | Article |
| Subject | Hematology Pediatrics, Perinatology and Child Health Oncology |
