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Genetic Dissection of Hypertension in Experimental Animal Models
| Content Provider | Scilit |
|---|---|
| Author | Mockrin, S. C. |
| Copyright Year | 1996 |
| Description | Experimental animal models are especially advantageous for genetic studies for several reasons. First, the use o f inbred animals eliminates the problem of genetic heterogeneity within a strain and in crosses between strains. Second, large numbers o f animals can be produced. Third, experimental animals can be extensively phenotyped. Finally, experimental animals have a shorter lifespan and display the disease phenotype within a few years, unlike patients, who typically show a late age o f onset, making collection o f patients and their parents harder. The loci identified in the experimental animal models can be used as candidate genes in the genetic dissection o f hypertension in man. Book Name: Molecular Genetics & Gene Therapy of Cardiovascular Diseases |
| Related Links | https://content.taylorfrancis.com/books/download?dac=C2006-0-04185-9&isbn=9780429077289&doi=10.1201/9781482273243-18&format=pdf |
| Ending Page | 340 |
| Page Count | 28 |
| Starting Page | 313 |
| DOI | 10.1201/9781482273243-18 |
| Language | English |
| Publisher | Informa UK Limited |
| Publisher Date | 1996-01-02 |
| Access Restriction | Open |
| Subject Keyword | Book Name: Molecular Genetics & Gene Therapy of Cardiovascular Diseases Peripheral Vascular Disease Hypertension Dissection Lifespan Inbred Experimental Animals Animal Models Experimental |
| Content Type | Text |
| Resource Type | Chapter |
