NDLI: Subthalamic nucleus and substantia nigra pars reticulata stimulation: the Grenoble experience

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Subthalamic nucleus and substantia nigra pars reticulata stimulation: the Grenoble experience

Content Provider	Scilit
Author	Benabid, Alim-Louis Koudsie, Adnan Chabardes, Stephan Vercueil, Laurent Benazzouz, Abdelhamid Minotti, Lorella Bas, Jean-François Le Kahane, Philippe Martin, Anne De Saint Hirsch, Edouard
Copyright Year	2020
Description	The objective of the Grenoble study was to provide alternative treatment for non-operable pharmaco-resistant epileptic patients. The subthalamic nucleus exerts an excitatory control on the nigral system. The surgical method was identical to the procedure used for the treatment of advanced Parkinson's disease cases by chronic stimula tion of subthalamic nucleus (STN). The STN is a target which is well known to neurostereotacti-cians in the movement disorders field. High frequency stimulation is a non-destructive method for target functional inhibition, already used extensively in parkinsonian patients and in dystonia. Electrodes were temporarily connected to a transcutaneous extension to allow recordings of EEG-type activity concomitantly with scalp EEG monitoring. Interictal spikes, as well as ictal epileptic discharges, were recorded simultaneously from all four electrode contacts. The preoperative seizure rat was 30 seizures per month. During the first weeks after surgery, there was no seizure, but the EEG showed persistent subclinical-clinical epileptiform discharges. Book Name: Deep Brain Stimulation and Epilepsy
Related Links	https://api.taylorfrancis.com/content/chapters/edit/download?identifierName=doi&identifierValue=10.1201/9781003076421-32&type=chapterpdf
Ending Page	348
Page Count	14
Starting Page	335
DOI	10.1201/9781003076421-32
Language	English
Publisher	Informa UK Limited
Publisher Date	2020-08-26
Access Restriction	Open
Subject Keyword	Book Name: Deep Brain Stimulation and Epilepsy Sport Sciences Treatment Stn Grenoble Seizure Nucleus Functional Discharges Eeg Stimulation Epileptic
Content Type	Text
Resource Type	Chapter

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