NDLI: The Development and Applications of Preparative-Scale Continuous Chromatography

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The Development and Applications of Preparative-Scale Continuous Chromatography

Content Provider	Scilit
Author	Barker, P. E. Ganetsos, G.
Copyright Year	2021
Description	The scaling up of continuous chromatography to production scale is considered. The various continuous countercurrent and crosscurrent chromatographic techniques have been reviewed and judged according to their merits. The latest developments on a preparative/production scale semicontinuous chromatographic refiner (SCCR), consisting of 12 columns each of 5.4 cm i.d. × 75 cm long and packed with calcium charged resin, are reported. When the production of high fructrose corn syrup was carried out using industrial barley syrup, product throughputs of 32.3 kg sugar solids/m3 resin/h were obtained, the fructose-rich product purity was over 90% with a concentration of 12.96% w/v, and glucose-rich product contained only 6.69% fructose and had a concentration of 25.4% w/v. The computer simulation of the SCCR's operation is reported, and a good fit with experimental data was obtained. Book Name: Preparative-Scale Chromatography
Related Links	https://api.taylorfrancis.com/content/chapters/edit/download?identifierName=doi&identifierValue=10.1201/9781003210108-12&type=chapterpdf
Ending Page	243
Page Count	25
Starting Page	219
DOI	10.1201/9781003210108-12
Language	English
Publisher	Informa UK Limited
Publisher Date	2021-07-29
Access Restriction	Open
Subject Keyword	Book Name: Preparative-scale Chromatography Fructose W/v Chromatographic Rich Syrup Scale Continuous Chromatography Sccr Product
Content Type	Text
Resource Type	Chapter

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