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Adherence to Subcutaneous Anti-TNF Treatment in Chronic Inflammatory Rheumatism and Therapeutic Patient Education
| Content Provider | Scilit |
|---|---|
| Author | Fayet, Françoise Fan, Angélique Rodere, Malory Savel, Carine Pereira, Bruno Soubrier, Martin |
| Copyright Year | 2020 |
| Description | Objective: Poor patient adherence to anti-TNF treatment has proven to be a major roadblock to effective management. Therapeutic patient education (TPE) is now recognized as a crucial tool in managing conditions like chronic inflammatory rheumatism and in improving treatment adherence. This study aimed to assess whether different TPE programs might improve adherence to subcutaneous anti-tumor necrosis factor (anti-TNF) treatment in patients with rheumatoid arthritis (RA), ankylosing spondyloarthritis (AS), and psoriatic arthritis (PsA). Methods: This was a retrospective, observational, monocentric study of current care practices. We included 193 patients (124 women; mean age 53.3 ± 14.8 years). All patients received subcutaneous anti-TNF treatment and one of three TPE models, delivered by a nurse, from 2009 to 2013. The cohort was grouped according to different educational models: M1: information (N=92); M2: individual TPE (N=80); and M3: individual and group TPE sessions (N=21). Adherence was assessed with the Morisky Medication Adherence Scale (MMAS-4™). Scores were rated as follows: good adherence (MMAS-4 = 4), moderate adherence (MMAS-4 = 2– 3), and poor adherence (MMAS-4 = 0– 1). Results: The mean disease duration was 10 years [95% CI: 5 to 18]. The cohort comprised 113 patients with RA, 73 with AS, and seven with PsA. Overall, 146 (75.7%) patients displayed good adherence, 34 (17.6%) displayed moderate adherence, and 13 (6.7%) displayed poor adherence. The M3 group displayed less adherence than the M1 and M2 groups. Old age was the only factor correlated with good adherence (p=0.005). The level of knowledge had no significant impact on adherence. Conclusion: This study demonstrated good adherence to anti-TNF treatment in patients that received TPE, particularly when it was delivered in individual sessions. |
| Related Links | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7047966/pdf https://www.dovepress.com/getfile.php?fileID=56333 |
| Ending Page | 369 |
| Page Count | 7 |
| Starting Page | 363 |
| ISSN | 1177889X |
| DOI | 10.2147/ppa.s240179 |
| Journal | Patient preference and adherence |
| Volume Number | 14 |
| Language | English |
| Publisher | Informa UK Limited |
| Publisher Date | 2020-02-01 |
| Access Restriction | Open |
| Subject Keyword | Journal: Patient Preference and Adherence Integrative and Complementary Medicine Chronic Inflammatory Rheumatism Subcutaneous Anti-tnf Therapeutic Education Treatment Adherence |
| Content Type | Text |
| Resource Type | Article |
| Subject | Social Sciences Pharmacology, Toxicology and Pharmaceutics Health Policy |
