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Significance of Adenosinetriphosphate in Human Sperm as Clinical Parameter
| Content Provider | Scilit |
|---|---|
| Author | Schlegel, W. Kusseler, R. Nieschlag, E. |
| Copyright Year | 1985 |
| Description | Washed human spermatozoa from 21 individuals with an average motility of 60% (quality index 277 ± 16) had an endogenous ATP generation of 7.5 ± 3.4 nmole/108spermatozoa. The ATP concentrations in spermatozoa from 16 patients with severely impaired motility of 26% (quality index 98 ± 13) was 16.9 ± 9.9 nmole/108spermatozoa. There was no correlation between ATP content and motility in either group. Sperm penetration into blood serum type AB, Rh-positive, was evaluated using a capillary tube penetration test. The penetration was graded with a maximum score of 14. Spermatozoa with an initial motility of 60% reached a score of 10 ± 0.7. After addition of 20 mmole of ATP the score was significantly improved to 13 ± 0.3. Compared with these results spermatozoa with an average motility of 26% reached a score of 4 ± 1. Exogenous ATP (20 mmole) increased the score to 8 ± 1.0. In both groups reduced glutathione had a negative effect. Human spermatozoa with high and low motility are capable to synthesize ATP. A dysfunction of the phosphorylating particles in the mitochondria appears not to be associated with low sperm motility. |
| Related Links | http://www.tandfonline.com/doi/pdf/10.3109/01485018508988294 |
| Ending Page | 176 |
| Page Count | 6 |
| Starting Page | 171 |
| ISSN | 01485016 |
| e-ISSN | 15210375 |
| DOI | 10.3109/01485018508988294 |
| Journal | Archives of andrology |
| Issue Number | 2-3 |
| Volume Number | 14 |
| Language | English |
| Publisher | Informa UK Limited |
| Publisher Date | 1985-01-01 |
| Access Restriction | Open |
| Subject Keyword | Journal: Archives of Andrology Endocrinology and Metabolism Reproductive Biology Human Sperm Clinical Parameter Sperm As Clinical Significance Adenosinetriphosphate in Human |
| Content Type | Text |
| Resource Type | Article |
| Subject | Endocrinology |
