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Manganese exposure among smelting workers: blood manganese-iron ratio as a novel tool for manganese exposure assessment.
| Content Provider | Scilit |
|---|---|
| Author | Cowan, Dallas M. Fan, Qiyuan Zou, Yan Shi, Xiujuan Chen, Jian Aschner, Michael Rosenthal, Frank S. Zheng, Wei |
| Copyright Year | 2009 |
| Description | Unexposed control subjects (n = 106), power distributing and office workers (n = 122), and manganese (Mn)-exposed ferroalloy smelter workers (n = 95) were recruited to the control, low and high groups, respectively. Mn concentrations in saliva, plasma, erythrocytes, urine and hair were significantly higher in both exposure groups than in the controls. The Fe concentration in plasma and erythrocytes, however, was significantly lower in Mn-exposed workers than in controls. The airborne Mn levels were significantly associated with Mn/Fe ratio (MIR) of erythrocytes (eMIR) (r = 0.77, p < 0.01) and plasma (pMIR) (r = 0.70, p < 0.01). The results suggest that the MIR may serve as a useful biomarker to distinguish Mn-exposed workers from the unexposed, control population. |
| Related Links | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3980868/pdf |
| ISSN | 1354750X |
| e-ISSN | 13665804 |
| DOI | 10.1080/13547500902730672 |
| Journal | Biomarkers |
| Issue Number | 1 |
| Volume Number | 14 |
| Language | English |
| Publisher | Informa UK Limited |
| Publisher Date | 2009-02-01 |
| Access Restriction | Open |
| Subject Keyword | Journal: Biomarkers Toxicology Manganese Iron Exposure Assessment Mn-fe Ratio Biomarker Saliva Erythrocyte Smelter |
| Content Type | Text |
| Resource Type | Article |
| Subject | Health, Toxicology and Mutagenesis Medicine Clinical Biochemistry Biochemistry |
