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The effect of flap thickness on corneal biomechanics after myopic laser in situ keratomileusis using the M-2 microkeratome
| Content Provider | Scilit |
|---|---|
| Author | Goussous, Iyad A. Agha, Mohamed-Sameh El Awadein, Ahmed Hosny, Mohamed H. Ghaith, Alaa A. Khattab, Ahmed L. |
| Copyright Year | 2017 |
| Abstract | The effect of flap thickness on corneal biomechanics after myopic laser in situ keratomileusis using the M-2 microkeratome Iyad A Goussous,1 Mohamed-Sameh El-Agha,1 Ahmed Awadein,1 Mohamed H Hosny,1 Alaa A Ghaith,2 Ahmed L Khattab2 1Department of Ophthalmology, Faculty of Medicine, Cairo University, Cairo, 2Faculty of Medicine, Alexandria University, Alexandria, Egypt Purpose: The purpose of this study was to determine the effect of flap thickness on corneal biomechanics after myopic laser in situ keratomileusis (LASIK).Methods: This is a prospective controlled non-randomized, institutional study. Patients underwent either epi-LASIK with mitomycin (advanced surface ablation [ASA]), thin-flap LASIK (90 µm head), or thick-flap LASIK (130 µm head). In ASA, the Moria Epi-K hydroseparator was used. LASIK flaps were created using the Moria M-2 mechanical microkeratome. The corneal hysteresis (CH) and corneal resistance factor (CRF) were measured preoperatively and 3 months after surgery, using the Ocular Response Analyzer®.Results: Ten patients (19 eyes) underwent ASA, 11 patients (16 eyes) underwent thin-flap LASIK, and 11 patients (16 eyes) underwent thick-flap LASIK. The mean preoperative CH was 10.47±0.88, 10.52±1.4, and 11.28±1.4 mmHg (p=0.043), respectively, decreasing after surgery by 1.75±1.02, 1.66±1.00, and 2.62±1.03 mmHg (p=0.017). The mean reduction of CH per micron of central corneal ablation was 0.031, 0.023, and 0.049 mmHg/µm (p=0.005). Mean preoperative CRF was 10.11±1.28, 10.34±1.87, and 10.62±1.76 mmHg (p=0.66), decreasing after surgery by 2.33±1.35, 2.77±1.03, and 2.92±1.10 mmHg (p=0.308). The mean reduction of CRF per micron of central corneal ablation was 0.039, 0.040, and 0.051 mmHg/µm (p=0.112).Conclusion: Thick-flap LASIK caused a greater reduction of CH and CRF than thin-flap LASIK and ASA, although this was statistically significant only for CH. ASA and thin-flap LASIK were found to be biomechanically similar. Keywords: flap thickness ectasia, hysteresis, LASIK, surface ablation |
| Related Links | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701557/pdf https://www.dovepress.com/getfile.php?fileID=39377 |
| Ending Page | 2071 |
| Page Count | 7 |
| Starting Page | 2065 |
| ISSN | 11775467 |
| e-ISSN | 11775483 |
| DOI | 10.2147/OPTH.S148216 |
| Journal | Clinical Ophthalmology |
| Volume Number | 11 |
| Language | English |
| Publisher | Informa UK Limited |
| Publisher Date | 2017-11-01 |
| Access Restriction | Open |
| Subject Keyword | Journal: Clinical Ophthalmology Ophthalmology Lasik Flap Thickness Ectasia Hysteresis Surface Ablation |
| Content Type | Text |
| Resource Type | Article |
| Subject | Ophthalmology |
