NDLI: Lithium Modulates Biochemical Circadian Rhythms in Wistar Rats

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Lithium Modulates Biochemical Circadian Rhythms in Wistar Rats

Content Provider	Scilit
Author	Subramanian, P. Menon, V. P. Arokiam, F. V. Rajakrishnan, V. Balamurugan, E.
Copyright Year	1998
Description	We studied the effects of chronic lithium treatment on circadian rhythms of glucose, cholesterol, calcium, potassium, malondialdehyde (MDA), and lactic acid in Wistar rats. Lithium altered the peak time, range, and 24h mean of these biochemical rhythms. Peak times of the circadian rhythms of glucose, calcium, and potassium were delayed by 3h, 6h, and 6h, respectively, whereas circadian rhythms of MDA and lactic acid were advanced by 9h and 3h, respectively, in lithium-treated rats. Delays observed in our experiments would support the hypothesis that lithium's therapeutic effect is to delay overtly fast circadian rhythms. Advances of peak times owing to lithium treatment are discussed.
Related Links	https://www.tandfonline.com/doi/pdf/10.3109/07420529808998667
Ending Page	38
Page Count	10
Starting Page	29
ISSN	07420528
e-ISSN	15256073
DOI	10.3109/07420529808998667
Journal	Chronobiology international
Issue Number	1
Volume Number	15
Language	English
Publisher	Informa UK Limited
Publisher Date	1998-01-01
Access Restriction	Open
Subject Keyword	Journal: Chronobiology International Biological Psychology Lithium Circadian Rhythm Glucose Lactic Acid Malondialdehyde
Content Type	Text
Resource Type	Article
Subject	Physiology Physiology (medical)

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