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Particulate Air Pollution and Osteoporosis: A Systematic Review
| Content Provider | Scilit |
|---|---|
| Author | Pang, Kok-Lun Ekeuku, Sophia Ogechi Chin, Kok-Yong |
| Copyright Year | 2021 |
| Description | Air pollution is associated with inflammation and oxidative stress, which predispose to several chronic diseases in human. Emerging evidence suggests that the severity and progression of osteoporosis are directly associated with inflammation induced by air pollutants like particulate matter (PM). This systematic review examined the relationship between PM and bone health or fractures. A comprehensive literature search was conducted from January until February 2021 using the PubMed, Scopus, Web of Science, Google Scholar and Cochrane Library databases. Human cross-sectional, cohort and case–control studies were considered. Of the 1500 papers identified, 14 articles were included based on the inclusion and exclusion criteria. The air pollution index investigated by most studies were $PM_{2.5}$ and $PM_{10}$. Current studies demonstrated inconsistent associations between PM and osteoporosis risk or fractures, which may partly due to the heterogeneity in subjects' characteristics, study design and analysis. In conclusion, there is an inconclusive relationship between osteoporosis risk and fracture and PM exposures which require further validation. |
| Related Links | https://www.dovepress.com/getfile.php?fileID=70936 |
| Ending Page | 2732 |
| Page Count | 18 |
| Starting Page | 2715 |
| ISSN | 11791594 |
| e-ISSN | 11791594 |
| DOI | 10.2147/rmhp.s316429 |
| Journal | Risk management and healthcare policy |
| Volume Number | 14 |
| Language | English |
| Publisher | Informa UK Limited |
| Publisher Date | 2021-06-01 |
| Access Restriction | Open |
| Subject Keyword | Journal: Risk Management and Healthcare Policy Endocrinology and Metabolism Particulate Matter Pm1 Pm2.5 Pm10 Bone Mineral Density Fracture |
| Content Type | Text |
| Resource Type | Article |
| Subject | Public Health, Environmental and Occupational Health Health Policy |
