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Role of Testosterone and Dihydrotestosterone in Spontaneous Gynecomastia of Adolescents
| Content Provider | Scilit |
|---|---|
| Author | Villalpando, Salvador Mondragón, L. Barrón, C. Pérez-Pastén, E. Castañleda, G. Alonso-Uriarte, R. Cortés-Gallegos, V. |
| Copyright Year | 1992 |
| Description | To test a possible hormonal mechanism of gynecomastia at puberty, a group of pubertal spontaneous gynecomastia (PSG) and healthy young volunteers (HYV), Tanner's stage II-V, were studied. Peripheral blood samples were obtained for measuring follicle stimulating hormone (FSH), luteinizing hormone (LH), prolactin (PRL), testosterone (T), dihydrotestosterone (DHT), estradiol (E-2) and estrone (E-1). No difference was established in steroids in pituitary hormonal concentration when both groups were compared on a sexual stage-matched control basis, except for T 2 SD in 5/9 subjects of PSG and DHT 2 SD in all of PSG. The T:DHT ratio varied from 5.0 to 15.4 in PSG and from 0.42 to 2.224 in HYV. Whether spontaneous gynecomastia might exist in an enzimatic blockade of 5 alpha-reductase and whether a decrease in the T:DHT ratio might favor the estrogen action for the progression of breast enlargement deserve further analysis. |
| Related Links | https://www.tandfonline.com/doi/pdf/10.3109/01485019208987695?needAccess=true http://www.tandfonline.com/doi/pdf/10.3109/01485019208987695 |
| Ending Page | 176 |
| Page Count | 6 |
| Starting Page | 171 |
| ISSN | 01485016 |
| e-ISSN | 15210375 |
| DOI | 10.3109/01485019208987695 |
| Journal | Archives of andrology |
| Issue Number | 3 |
| Volume Number | 28 |
| Language | English |
| Publisher | Informa UK Limited |
| Publisher Date | 1992-01-01 |
| Access Restriction | Open |
| Subject Keyword | Journal: Archives of Andrology Endocrinology and Metabolism Dihydrotestosterone Psg Hormonal Hyv Spontaneous Gynecomastia Dht Ratio |
| Content Type | Text |
| Resource Type | Article |
| Subject | Endocrinology |
