NDLI: Continuous Granulation

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Continuous Granulation

Content Provider	Scilit
Author	Vervaet, Chris Beer, Thomas De Vanhoorne, Valérie
Copyright Year	2021
Description	This chapter discusses the continuous processing of pharmaceutical solid dosage forms, focusing on continuous wet granulation. Based on the advantages offered by continuous manufacturing, it highlights the drivers for the pharmaceutical industry to shift from batch to continuous processing. It reviews the techniques that allow continuous wet granulation of pharmaceuticals: fluid-bed granulation, twin-screw granulation, and ring layer granulation. For continuous twin-screw granulation – the most commonly used continuous wet granulation technique – the process parameters affecting the critical quality attributes of the granules are discussed. The currently available integrated continuous manufacturing lines with process analytical technology (PAT) technology for monitoring and control of granule quality are presented. Book Name: Handbook of Pharmaceutical Granulation Technology
Related Links	https://api.taylorfrancis.com/content/chapters/edit/download?identifierName=doi&identifierValue=10.1201/9780429320057-13-15&type=chapterpdf
Ending Page	465
Page Count	21
Starting Page	445
DOI	10.1201/9780429320057-13-15
Language	English
Publisher	Informa UK Limited
Publisher Date	2021-04-02
Access Restriction	Open
Subject Keyword	Book Name: Handbook of Pharmaceutical Granulation Technology Biomedical Engineering Manufacturing Pharmaceutical Twin Screw Continuous Wet Granulation
Content Type	Text
Resource Type	Chapter

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