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High coronary calcium score and post-procedural CK-MB are noninvasive predictors of coronary stent restenosis
| Content Provider | Scilit |
|---|---|
| Author | Lee, Jae-Beom Choi, Yun-Seok Chung, Woo-Baek Kwon, Ami Park, Chul-Soo Lee, Man-Young |
| Copyright Year | 2017 |
| Description | High coronary calcium score and post-procedural CK-MB are noninvasive predictors of coronary stent restenosis Jae-Beom Lee,1 Yun-Seok Choi,2 Woo-Baek Chung,2 Ami Kwon,2 Chul-Soo Park,2 Man-Young Lee2 1Anyang Sam Hospital, 2Division of Cardiology, Department of Internal Medicine, Youido St Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea Purpose: High coronary calcium score (CCS) and post-procedural cardiac enzyme may be related with poor outcomes in patients with coronary stent implantation. Methods: A total of 1,072 patients (63.2% male, mean age: 61.7±10.3 years) who underwent coronary multi-detect computed tomography at index procedure and follow-up coronary angiography (CAG) after drug-eluting stent (DES) were divided into two groups: those with and without target lesion revascularization (TLR; >50% reduction in luminal stent diameter or angina symptoms on follow-up CAG). The CCSs for predicting stent revascularization were elucidated. Results: There were no significant differences between the two groups with regard to risk factors. The initial CCS was significantly higher in the TLR group (1,102.4±743.7 vs 345.8±51.05, P=0.04). After adjustment of significant factors for TLR, only CCS and post-procedural creatine kinase MB form (CK-MB) elevation were significant predictors of coronary artery TLR. Receiver operation curve revealed that >800 in CCS had 69% in sensitivity and 88% in specificity about predicting the TLR. Conclusion: High CCS with post-procedural CK-MB might be the useful predictors for TLR after DES implantation. Keywords: coronary restenosis, drug-eluting stents, calcium, creatine kinase |
| Related Links | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5322937/pdf https://www.dovepress.com/getfile.php?fileID=34983 |
| Ending Page | 404 |
| Page Count | 6 |
| Starting Page | 399 |
| ISSN | 11769092 |
| e-ISSN | 11781998 |
| DOI | 10.2147/cia.s125592 |
| Journal | Clinical interventions in aging |
| Volume Number | 12 |
| Language | English |
| Publisher | Informa UK Limited |
| Publisher Date | 2017-02-01 |
| Access Restriction | Open |
| Subject Keyword | Journal: Clinical Interventions in Aging Peripheral Vascular Disease Calcium Coronary Restenosis Creatine Kinase Drug-eluting Stents |
| Content Type | Text |
| Resource Type | Article |
| Subject | Geriatrics and Gerontology |
