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Mucoadhesive Drug Delivery Systems
| Content Provider | Scilit |
|---|---|
| Author | Jiménez-Castellanos, Ma Rosa Zia, Hussein Rhodes, C. T. |
| Copyright Year | 1993 |
| Description | Pharmaceutical aspects of mucoadhesion have been the subject of great interest during recent years because mucoadhesion could be a solution for bioavailability problems that result from a too short length of stay of the pharmaceutical dosage form at the absorption site within the gastro-intestinal tract. This paper describes some aspects of bioadhesion such as mucus structure, stages of adhesion and the theories proposed that attempt to explain the adhesion mechanism. The factors that affect the bioadhesive power of a polymer, the methods that permit the evaluation of a bioadhesive system and the methods for surface characterization of biomaterials are discussed. Finally, the various polymers used and the bioadhesive systems designed for several therapeutic purposes are presented. |
| Related Links | http://www.tandfonline.com/doi/pdf/10.3109/03639049309038765 |
| Ending Page | 194 |
| Page Count | 52 |
| Starting Page | 143 |
| ISSN | 03639045 |
| e-ISSN | 15205762 |
| DOI | 10.3109/03639049309038765 |
| Journal | Drug Development and Industrial Pharmacy |
| Issue Number | 1-2 |
| Volume Number | 19 |
| Language | English |
| Publisher | Informa UK Limited |
| Publisher Date | 1993-01-01 |
| Access Restriction | Open |
| Subject Keyword | Journal: Drug Development and Industrial Pharmacy Biomedical Engineering Bioavailability Absorption Interest Mucoadhesion Mucus Stay Attempt Gastro Great |
| Content Type | Text |
| Resource Type | Article |
| Subject | Organic Chemistry Drug Discovery Pharmacology Pharmaceutical Science |
