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Cellular Regeneration and Recovery of the Maxillary Sinus Mucosa:An Experimental Study in Rabbits
| Content Provider | Scilit |
|---|---|
| Author | Norlander, Tomas Forsgren, Karin Stierna, Jan Kumlien Pontus Carlsöö, Bengt |
| Copyright Year | 1992 |
| Description | Unilateral maxillary sinusitis was induced in 30 New Zealand White rabbits with Streptococcus pneumoniae or Bacteroides fragilis. In another group of 15 rabbits without infection, the sinus mucosa was surgically removed in defined areas. In both series, the sinuses were serially sectioned for histological analysis of the cellular regenerative capacity. In maxillary sinusitis induced by Bacteroides fragilis, an inflammatory and also reparative process involving all mucosal layers including the underlying periosteum was seen. The more superficial trauma as found in pneumococcal sinusitis eventually led to restitution ad integrum. Following surgical removal, the denuded sinus-lining was reepithelized by a flattened ciliated epithelium on a lamina propria displaying fibrosis and lacking serous glands. The restoration of the rabbit maxillary sinus mucosa after surgical trauma thus leads to structural abnormalities of the epithelium as well as the lamina propria, and these changes are likely to interfere with the normal function of the sinus mucosa. |
| Related Links | http://www.tandfonline.com/doi/pdf/10.3109/00016489209136805 |
| Ending Page | 37 |
| Page Count | 5 |
| Starting Page | 33 |
| ISSN | 00016489 |
| e-ISSN | 16512251 |
| DOI | 10.3109/00016489209136805 |
| Journal | Acta Oto-Laryngologica |
| Issue Number | sup492 |
| Volume Number | 112 |
| Language | English |
| Publisher | Informa UK Limited |
| Publisher Date | 1992-01-01 |
| Access Restriction | Open |
| Subject Keyword | Journal: Acta Oto-laryngologica Dentistry and Oral Surgery New Zealand Rabbits Sinusitis Maxillary Sinus Mucosa Lamina |
| Content Type | Text |
| Resource Type | Article |
| Subject | Otorhinolaryngology |