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Constitutive Heterochromatin Polymorphisms in Children with Acute Lymphoblastic Leukemia
| Content Provider | Scilit |
|---|---|
| Author | Tsezoil, Aspasia Kitsiou-Tzeli, Sofia Kosmidis, Helen Paidousi, Kalliopi Katsouyanni, Klea Sinaniotis, Constantine |
| Copyright Year | 1993 |
| Description | The C-band heterochromatin polymorphisms of chromosomes 1, 9, and 16 were studied on peripheral lymphocytes of 67 children with acute lymphoblastic leukemia (ALL) and 50 control individuals. A statistically significant difference between patients and controls was found for large heterochromatin regions (level 3) of chromosomes 1 and 9 (P > 0.001) and for small heterochromatin regions (level 1) of chromosome 16 (P > 0.001). The patients also showed a significant increase in chromosomes 1 and 9 heteromorphism with respect to controls (P > 0.001). |
| Related Links | http://www.tandfonline.com/doi/pdf/10.3109/08880019309016522 |
| ISSN | 08880018 |
| e-ISSN | 15210669 |
| DOI | 10.3109/08880019309016522 |
| Journal | Pediatric hematology and oncology |
| Issue Number | 1 |
| Volume Number | 10 |
| Language | English |
| Publisher | Informa UK Limited |
| Publisher Date | 1993-01-01 |
| Access Restriction | Open |
| Subject Keyword | Journal: Pediatric Hematology and Oncology Pediatrics and Child Health Polymorphism |
| Content Type | Text |
| Resource Type | Article |
| Subject | Hematology Pediatrics, Perinatology and Child Health Oncology |