Loading...
Please wait, while we are loading the content...
Similar Documents
Angiotensin Converting Enzyme Activity in the Amygdaloid Complex in A Neurogenic Hypertensive Model
| Content Provider | Scilit |
|---|---|
| Author | Dabsys, Susana M. Balda, Maria S. Pirola, Carlos J. Finkielman, Samuel Nahmod, Victor E. |
| Copyright Year | 1988 |
| Description | The bilateral destruction of the ventral noradrenergic pathway induced by 6-hydroxydopamine (6-OHDA) administration into the ventral pons led to an increase in arterial blood pressure (ABP) and norepinephrine depletion in the amygdaloid complex, nucleus accumbens, septal area and olfactory bulb. Specific angiotensin converting enzyme (ACE) activity was significantly increased only in the amygdaloid complex (Control: 4.56 ± 0.95; Vehicle: 4.08 ± 1.07; 6-OHDA: 11.76 ± 1.84). A significant correlation between arterial blood pressure and specific ACE activity levels in the amygdaloid complex was observed (r: 0.775; p < 0.002). These results suggest that an increase in specific ACE activity of the amygdaloid complex after norepinephrine depletion could play a role in the development of hypertension in this model. |
| Related Links | http://www.tandfonline.com/doi/pdf/10.3109/10641968809033913 |
| Ending Page | 615 |
| Page Count | 11 |
| Starting Page | 605 |
| ISSN | 07300077 |
| DOI | 10.3109/10641968809033913 |
| Journal | Clinical and Experimental Hypertension. Part A: Theory and Practice |
| Issue Number | 4 |
| Volume Number | 10 |
| Language | English |
| Publisher | Informa UK Limited |
| Publisher Date | 1988-01-01 |
| Access Restriction | Open |
| Subject Keyword | Journal: Clinical and Experimental Hypertension. Part A: Theory and Practice Peripheral Vascular Disease Angiotensin Converting Enzyme Amygdaloid Complex Neurogenic Hypertensive Hypertensive Model |
| Content Type | Text |
| Resource Type | Article |
| Subject | Internal Medicine |
