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Central Nervous System Disease in Childhood Acute Lymphoblastic Leukemia: Prognostic Factors and Results of Treatment
| Content Provider | Scilit |
|---|---|
| Author | Kreuger, A. Garwicz, S. Hertz, H. Jonmundsson, C. Latining, M. Lie, S. O. Moe, P. J. Salmi, T. T. Schröder, H. Siimes, M. A. Wesenberg, F. Yssing, M. Åhström, L. Gustafsson, G. |
| Copyright Year | 1991 |
| Description | (years) revealed that isolated CNS relapse had occurred in 70 children (9.0%). Of these 70 patients, 12 out of 142 children (8.5%) had initially received irradiation and 58 out of 628 children (9.2%) only chemotherapy as CNS-prophylaxis. There was a significant higher risk for boys (12%) than for girls (6%) to relapse in the CNS compartment. Unfavorable prognostic factors for survival after isolated CNS relapse were short duration of first remission and male sex. In high-risk patients after an isolated CNS relapse, there was no difference in prognosis related to treatment with or without irradiation as initial CNS prophylaxis. |
| Related Links | http://www.tandfonline.com/doi/pdf/10.3109/08880019109028802 |
| Ending Page | 299 |
| Page Count | 9 |
| Starting Page | 291 |
| ISSN | 08880018 |
| e-ISSN | 15210669 |
| DOI | 10.3109/08880019109028802 |
| Journal | Pediatric hematology and oncology |
| Issue Number | 4 |
| Volume Number | 8 |
| Language | English |
| Publisher | Informa UK Limited |
| Publisher Date | 1991-01-01 |
| Access Restriction | Open |
| Subject Keyword | Journal: Pediatric Hematology and Oncology Pediatrics and Child Health Central Nervous System |
| Content Type | Text |
| Resource Type | Article |
| Subject | Hematology Pediatrics, Perinatology and Child Health Oncology |