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Association of Vitamin D with outcome after intra cytoplasmic sperm injection
| Content Provider | Scilit |
|---|---|
| Author | Abdullah, Umme Hani Lalani, Salima Syed, Fatima Arif, Sara Rehman, Rehana |
| Copyright Year | 2016 |
| Description | Objective: To observe effects of vitamin D levels on pregnancy outcome after intra cytoplasmic sperm injection (ICSI). Method: It was a cross sectional study conducted in Australian Concept Infertility Medical Centre from July 2011 to August 2014. Estimation of 25-hydroxy cholecalciferol (25-OHD) of consented females (252) was done before treatment protocol for ICSI. Results of β hCG performed 14 days after embryo transfer categorized groups; Pregnant with ß hCG more than 25 IU/mL and rest included in non-pregnant group. Both groups were compared by independent sample t-test and Pearson Chi Square test. Binary Logistic Regression Analysis was used to estimate odds ratio of pregnancy outcome with its predictors including Vitamin D. Results: The mean value of 25-OHD, number of oocytes, fertilized oocytes and endometrial thickness was significantly higher in pregnant women. A significant positive association of 25-OHD with clinical pregnancy and thickness of endometrium was observed. After adjustment with female age and BMI, positive association of vitamin D with endometrial thickness was observed. Conclusion: Deficiency of 25-OHD in females hinders the accomplishment of optimal endometrial thickness required for implantation of embryo after ICSI. The improvement in vitamin D status can thus improve success results in assisted reproductive clinics. |
| Related Links | http://www.tandfonline.com/doi/pdf/10.3109/14767058.2016.1163680 |
| Ending Page | 120 |
| Page Count | 4 |
| Starting Page | 117 |
| ISSN | 14767058 |
| e-ISSN | 14764954 |
| DOI | 10.3109/14767058.2016.1163680 |
| Journal | The Journal of Maternal-Fetal & Neonatal Medicine |
| Issue Number | 1 |
| Volume Number | 30 |
| Language | English |
| Publisher | Informa UK Limited |
| Publisher Date | 2016-04-14 |
| Access Restriction | Open |
| Subject Keyword | Journal: The Journal of Maternal-fetal & Neonatal Medicine Andrology Infertility Vitamin D Assisted Reproductive Techniques (art) Intracytoplasmic Sperm Injection (icsi) |
| Content Type | Text |
| Resource Type | Article |
| Subject | Pediatrics, Perinatology and Child Health Obstetrics and Gynecology |