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Bovine Cervical Mucus Penetration by Human Spermatozoa: Lack of Association with Conception
| Content Provider | Scilit |
|---|---|
| Author | Marshburn, P. B. Dodson, W. C. Haney, A. F. |
| Copyright Year | 1989 |
| Description | Penetration of bovine cervical mucus (BCMP) by human spermatozoa has been reported to be a test that may aid in assessment of male fertility. We determined the predictive value of BCMP for conception in 127 infertile couples. Fresh semen and swim-up specimens were tested with the Penetrak® assay. Out of 127 patients 16 (13%) achieved pregnancy with 6 months to 2 years of follow-up. In the 62 men with sperm counts of >20 million/ml and motility of >60%, 55 (89%) had adequate BCMP while adequate penetration was found in only eight of 24 (33%) with both sperm count and motility below these values (p < 0.001). A normal BCMP did not predict pregnancy, and a reduced BCMP had no prognostic value in designating couples not likely to conceive. The comparison of penetration values for semen following swim-up suggests that this preparation may improve the correlation of BCMP with fertility. These results indicate that the semen parameters of sperm density and percent motility predicted spermatozoal performance in the BCMP assay, and that the assessment of BCMP did not predict the likelihood of pregnancy. |
| Related Links | http://www.tandfonline.com/doi/pdf/10.3109/01485018908986747 |
| Ending Page | 34 |
| Page Count | 6 |
| Starting Page | 29 |
| ISSN | 01485016 |
| e-ISSN | 15210375 |
| DOI | 10.3109/01485018908986747 |
| Journal | Archives of andrology |
| Issue Number | 1 |
| Volume Number | 22 |
| Language | English |
| Publisher | Informa UK Limited |
| Publisher Date | 1989-01-01 |
| Access Restriction | Open |
| Subject Keyword | Journal: Archives of Andrology Endocrinology and Metabolism Reproductive Biology Human Spermatozoa Cervical Mucus Penetration Bovine Cervical |
| Content Type | Text |
| Resource Type | Article |
| Subject | Endocrinology |
