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In vitro activity of amphotericin B, itraconazole, terbinafine and 5-fluocytosine against Exophiala spinifera and evaluation of post-antifungal effects
| Content Provider | Scilit |
|---|---|
| Author | Vitale, R. G. Hoog, G. S. De Verweij, Paul E. |
| Copyright Year | 2003 |
| Description | Antifungal susceptibility profiles were determined for 16 strains of the black yeast Exophiala spinifera applying different temperature regimens. Fluconazole was the least effective in vitro. Lowest minimal inhibitory concentration (MIC) values were found with itraconazole. The activities of antifungal agents against environmental and clinical strains were similar. Post-antifungal effect (PAFE) of four drugs was determined for 11 clinical strains. PAFE was observed only for amphotericin B, with extended inhibition times seen at high drug concentrations. |
| Related Links | https://academic.oup.com/mmy/article-pdf/41/4/301/3275936/41-4-301.pdf |
| Ending Page | 307 |
| Page Count | 7 |
| Starting Page | 301 |
| ISSN | 13693786 |
| DOI | 10.1080/13693780310001600822 |
| Journal | Medical mycology |
| Issue Number | 4 |
| Volume Number | 41 |
| Language | English |
| Publisher | Informa UK Limited |
| Publisher Date | 2003-01-01 |
| Access Restriction | Open |
| Subject Keyword | Journal: Medical Mycology Mycology Amphotericin B Antifungal Agents Exophiala Itraconazole Terbinafine Drug Concentration Minimum Inhibitory Concentration Measurement Yeasts Body Temperature Temperature Fluconazole |
| Content Type | Text |
| Resource Type | Article |
| Subject | Infectious Diseases Veterinary |