NDLI: Response of Synovial Immunocytes to Intra-Articular Agents in Experimental Arthritis

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Response of Synovial Immunocytes to Intra-Articular Agents in Experimental Arthritis

Content Provider	Scilit
Author	Isomäki, A. M. Oka, M. Pitkänen, R. Rantala, I.
Copyright Year	1975
Description	In rabbits with immune arthritis the numbers of lymphoid aggregates and pyroninophilic and non-pyroninophilic cells per unit area of synovium were calculated from sections taken at various intervals after intraarticular drug injections. A model of immune arthritis based on the results is presented. In the active phase of the arthritis, plasma cells, plasmablasts and lymphoid aggregates proliferate, while the number of lymphocytes decreases. In the inactive phase after treatment, the cell pattern is the reverse. The ratio of pyroninophilic to non-pyroninophilic cells proved to be a good measure of the activity of the arthritis. A favourable therapeutic effect was achieved with triamcinolone hexacetonide and combined steroid-osmic acid, but not with osmic acid alone.
Related Links	http://www.tandfonline.com/doi/pdf/10.3109/03009747509165442
Ending Page	133
Page Count	5
Starting Page	129
ISSN	03009742
e-ISSN	15027732
DOI	10.3109/03009747509165442
Journal	Scandinavian Journal of Rheumatology
Issue Number	3
Volume Number	4
Language	English
Publisher	Informa UK Limited
Publisher Date	1975-01-01
Access Restriction	Open
Subject Keyword	Journal: Scandinavian Journal of Rheumatology Cell Tissue Engineering Experimental Arthritis Intra Articular Articular Agents Synovial Immunocytes
Content Type	Text
Resource Type	Article
Subject	Immunology and Allergy Immunology Rheumatology

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