NDLI: Cu-Catalyzed C–H Activation Reaction: One-Pot Direct Synthesis of Xanthine and Uric Acid Derivatives from 5-Bromouracil

Content Provider	Scilit
Author	Roy∗, Brindaban Rahaman∗, Habibur Hazra, Somjit Mondal, Biplab
Copyright Year	2021
Description	A one-pot direct synthesis of xanthine and uric acid derivates is reported. This simple yet efficient methodology illustrates concurrent formation of two C–N bonds using $CuBr_{2}$ as catalyst and one of those C–N bonds is formed by uracil C6–H bond activation. Received: 25 May 2021 Accepted after revision: 02 July 2021 Accepted Manuscript online: 02 July 2021 Article published online: 23 July 2021 © 2021. Thieme. All rights reserved Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, Germany
Related Links	http://www.thieme-connect.de/products/ejournals/pdf/10.1055/a-1542-9683.pdf
Ending Page	1761
Page Count	5
Starting Page	1757
ISSN	09365214
e-ISSN	14372096
DOI	10.1055/a-1542-9683
Journal	Synlett
Issue Number	17
Volume Number	32
Language	English
Publisher	Georg Thieme Verlag KG
Publisher Date	2021-07-02
Access Restriction	Open
Subject Keyword	Journal: Synlett Organic Chemistry C–h Activation C–n Bond Formation Uric Acids One-pot Cyclization
Content Type	Text
Resource Type	Article
Subject	Organic Chemistry

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Cu-Catalyzed C–H Activation Reaction: One-Pot Direct Synthesis of Xanthine and Uric Acid Derivatives from 5-Bromouracil