NDLI: Concise Three-Step Strategy for the Synthesis of 2-Benzoxepin-3(1H)-ones

Content Provider	Scilit
Author	Satyanarayana, Gedu Madhurima, Hazra Krishna, Jonnada
Copyright Year	2015
Description	A short and efficient method was developed for the synthesis of 2-benzoxepin-3(1H)-ones. The synthetic sequence comprises of initial intermolecular Heck coupling, followed by reduction of the carbonyl functionality of the Heck product and finally base-induced intramolecular condensation. Notably, the final condensation may proceed by an interesting oxy-Michael addition, cycloreversion via double bond isomerization and intramolecular condensation.
Related Links	http://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-0034-1379901.pdf
Ending Page	1254
Page Count	10
Starting Page	1245
ISSN	00397881
e-ISSN	1437210X
DOI	10.1055/s-0034-1379901
Journal	Synthesis
Issue Number	09
Volume Number	47
Language	English
Publisher	Georg Thieme Verlag KG
Publisher Date	2015-03-18
Access Restriction	Open
Subject Keyword	Journal: Synthesis Organic Chemistry Palladium Catalysis
Content Type	Text
Resource Type	Article
Subject	Organic Chemistry Catalysis

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Concise Three-Step Strategy for the Synthesis of 2-Benzoxepin-3(1H)-ones