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Severe Progressive Brain Atrophy in Pediatric Multiple Sclerosis
| Content Provider | Scilit |
|---|---|
| Author | Buyukturkoglu, Korhan Inglese, Matilde Wollack, Jan B. Balashov, Konstantin Bhise, Vikram |
| Copyright Year | 2015 |
| Description | Background Multiple sclerosis (MS) is an immune-mediated disease of the central nervous system. Progressive brain atrophy is a known marker of patient disability and cognitive impairment in MS patient, but limited information is available about the clinical and cognitive consequences in the pediatric population. Case Report We present a case of aggressive pediatric-onset MS with severe rapidly progressive brain atrophy, neurological disability, and cognitive deterioration. Serial brain magnetic resonance imaging studies demonstrate ongoing cerebral atrophy correlating with severe deficits on serial neuropsychological testing. Conclusion A subset of pediatric MS patient may be vulnerable to severe cognitive deterioration associated with marked brain atrophy. |
| Related Links | http://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-0036-1579645.pdf |
| Ending Page | 035 |
| Page Count | 4 |
| Starting Page | 032 |
| ISSN | 13096680 |
| e-ISSN | 13096745 |
| DOI | 10.1055/s-0036-1579645 |
| Journal | Journal of Pediatric Neuroradiology |
| Issue Number | 02 |
| Volume Number | 04 |
| Language | English |
| Publisher | Georg Thieme Verlag KG |
| Publisher Date | 2015-06-01 |
| Access Restriction | Open |
| Subject Keyword | Journal: Journal of Pediatric Neuroradiology Clinical Neurology Magnetic Resonance Imaging |
| Content Type | Text |
| Resource Type | Article |
| Subject | Radiology, Nuclear Medicine and Imaging Neurology (clinical) Pediatrics, Perinatology and Child Health |