Loading...
Please wait, while we are loading the content...
Similar Documents
Anti-Inflammatory Activity of Gallic Acid
| Content Provider | Scilit |
|---|---|
| Author | van Dijk, H. |
| Editor | Kroes, B. H. Berg, A. J. J. Van Den van Ufford, H. C. Quarles Labadie, R. P. |
| Copyright Year | 1992 |
| Description | Gallic acid was found to possess anti-inflammatory activity towards zymosan-induced acute food pad swelling in mice. In vitro studies on the mode of action of gallic acid revealed that this compound interferes with the functioning of polymorphonuclear leukocytes (PMNs). Scavenging of superoxide anions, inhibition of myeloperoxidase release and activity as well as a possible interference with the assembly of active NADPH-oxidase may account for the inhibition of inflammatory process by gallic acid. Structure-activity relationship analysis showed that the o-dihydroxy group of gallic acid is important for the inhibitory activity in vitro. |
| Related Links | http://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-2006-961535.pdf |
| Ending Page | 504 |
| Page Count | 6 |
| Starting Page | 499 |
| ISSN | 00320943 |
| e-ISSN | 14390221 |
| DOI | 10.1055/s-2006-961535 |
| Journal | Planta Medica |
| Issue Number | 06 |
| Volume Number | 58 |
| Language | English |
| Publisher | Georg Thieme Verlag KG |
| Publisher Date | 1992-12-01 |
| Access Restriction | Open |
| Subject Keyword | Journal: Planta Medica Integrative and Complementary Medicine Anti-inflammatory Activity Chemiluminescence. |
| Content Type | Text |
| Resource Type | Article |
| Subject | Organic Chemistry Drug Discovery Analytical Chemistry Molecular Medicine Pharmacology Complementary and Alternative Medicine Pharmaceutical Science |
