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Practical and Efficient Synthesis of (E)-α,β-Unsaturated Amides Bearing (S)-α-Methylbenzylamine from 2-Phosphonamides via Horner-Wadsworth-Emmons Reaction
| Content Provider | Scilit |
|---|---|
| Author | Ordóñez, Mario Hernández-Fernández, Eugenio Fernández-Zertuche, Mario García-Barradas, Oscar Muñoz-Muñiz, Omar |
| Copyright Year | 2006 |
| Description | The highly stereoselective synthesis of (E)-α,β-unsaturated amides bearing (S)-α-methylbenzylamine was achieved from 2-phosphonamides via Horner-Wadsworth-Emmons reaction. The starting phosphonamides are easily prepared in two steps with excellent yields via the standard Arbuzov reaction of trimethylphosphite and α-bromoamides. |
| Related Links | http://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-2006-926265.pdf |
| Ending Page | 0444 |
| Page Count | 5 |
| Starting Page | 0440 |
| ISSN | 09365214 |
| e-ISSN | 14372096 |
| DOI | 10.1055/s-2006-926265 |
| Journal | Synlett |
| Issue Number | 03 |
| Volume Number | 2006 |
| Language | English |
| Publisher | Georg Thieme Verlag KG |
| Publisher Date | 2006-02-06 |
| Access Restriction | Open |
| Subject Keyword | Organic Chemistry Β-unsaturated Amides Chiral Phosphonamides horner-wadsworth-emmons Reaction (s)-α-methylbenzylamine |
| Content Type | Text |
| Resource Type | Article |
| Subject | Organic Chemistry |