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A New Synthesis of Ammonium 3-Deoxy-D-manno-octulosonate (Ammonium KDO) from D-Lyxose
| Content Provider | Scilit |
|---|---|
| Author | Giese, B. Linker, T. |
| Copyright Year | 1992 |
| Description | The ammonium salt of 3-deoxy-D-manno-2-octulosonic acid (10) is synthesized from D-lyxose (2) via 1,2,3,4-tetra-O-acetyl-5-bromo-α-D-lyxopyranose (3) and radical C,C-bond formation with tert-butyl 2-(tributylstannylmethyl) propenoate (6). After deprotection and reduction, ozonolysis of 2,3-dideoxy-2-methylene -D-manno-octonic acid (9) yields the target molecule 10. |
| Related Links | http://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-1992-34178.pdf |
| Ending Page | 48 |
| Page Count | 3 |
| Starting Page | 46 |
| ISSN | 00397881 |
| e-ISSN | 1437210X |
| DOI | 10.1055/s-1992-34178 |
| Journal | Synthesis |
| Issue Number | 1/2 |
| Volume Number | 1992 |
| Language | English |
| Publisher | Georg Thieme Verlag KG |
| Publisher Date | 1992-01-01 |
| Access Restriction | Open |
| Subject Keyword | Journal: Synthesis Organic Chemistry Tributylstannylmethyl |
| Content Type | Text |
| Resource Type | Article |
| Subject | Organic Chemistry Catalysis |