NDLI: Synthesis and Antiviral Evaluation of Sugar Uracil-1-ylmethylhydrazones and Their Oxadiazoline Derivatives

Content Provider	Scilit
Author	Ali, Omar M. Amer, Hamada H.
Editor	Abdel-Rahman, Adel A. -H.
Copyright Year	2007
Description	1-Carbethoxymethyluracils have been synthesized and derivatized to the corresponding hydrazides, which were reacted with monosaccharides to afford the corresponding sugar hydrazones. Acetylation of the latter with acetic anhydride in pyridine, afforded the per-O-acetyl derivatives, while heating in acetic anhydride gave the corresponding oxadiazolines. The prepared compounds were tested for antiviral activity against hepatitis B virus and showed moderate activities.
Related Links	http://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-2007-983878.pdf
Ending Page	2828
Page Count	6
Starting Page	2823
ISSN	00397881
e-ISSN	1437210X
DOI	10.1055/s-2007-983878
Journal	Synthesis
Issue Number	18
Volume Number	2007
Language	English
Publisher	Georg Thieme Verlag KG
Publisher Date	2007-08-29
Access Restriction	Open
Subject Keyword	Journal: Synthesis Organic Chemistry
Content Type	Text
Resource Type	Article
Subject	Organic Chemistry Catalysis

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