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Long-Term Results of Surgical Management of Pulmonary Metastases from Renal Cell Carcinoma
| Content Provider | Scilit |
|---|---|
| Author | Marulli, G. Sartori, F. Rea, F. |
| Editor | Bassi, P. F. Moro, F. Dal Favaretto, A. Gino |
| Copyright Year | 2006 |
| Description | Background: Metastatic renal cell carcinoma (RCC) has a poor prognosis and conventional treatments such as chemoradiotherapy show little efficacy. Surgical resection of pulmonary metastases from RCC is a widely accepted treatment, even if selection criteria based on prognostic factors have still not been defined. The aim of this study was to determine the long-term survival, clinical outcome and prognostic factors after surgery. Methods: Between 1988 and 2004, 59 patients underwent resection of pulmonary metastases from RCC. Univariate and multivariate analysis of prognostic factors was carried out. Results: Complete resection was achieved in 54 (91.5 %) patients. No intra- or postoperative mortality occurred, 5 (8.5 %) patients experienced postoperative complications. Overall, the 1-, 3-, and 5-year survival rates were 86.5 %, 63 % and 53 %, respectively. Age at the time of pulmonary resection was found to be the only independent factor influencing prognosis. Conclusion: Pulmonary resection of metastases from RCC is a safe and effective treatment associated with a low morbidity and mortality and with high long-term survival. The lack of other effective therapies suggests use of the surgical approach whenever possible. |
| Related Links | http://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-2006-924414.pdf |
| Ending Page | 547 |
| Page Count | 4 |
| Starting Page | 544 |
| ISSN | 01716425 |
| e-ISSN | 14391902 |
| DOI | 10.1055/s-2006-924414 |
| Journal | The Thoracic and Cardiovascular Surgeon |
| Issue Number | 8 |
| Volume Number | 54 |
| Language | English |
| Publisher | Georg Thieme Verlag KG |
| Publisher Date | 2006-12-06 |
| Access Restriction | Open |
| Subject Keyword | Journal: The Thoracic and Cardiovascular Surgeon Renal Cell Carcinoma Pulmonary Metastases Surgical Resection |
| Content Type | Text |
| Resource Type | Article |
| Subject | Pulmonary and Respiratory Medicine Surgery Cardiology and Cardiovascular Medicine |