NDLI: Prevention of Venous Thromboembolism in Cancer Patients

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Prevention of Venous Thromboembolism in Cancer Patients

Content Provider	Scilit
Author	Kakkar, Ajay K.
Editor	Williamson, Robin C. N.
Copyright Year	1999
Description	Thrombosis is a common complication in patients with malignancy and its occurrence is heightened by therapeutic interventions such as operations or the use of chemotherapy. The magnitude of the risk for venous thromboembolism (VTE) is well established for cancer surgery where rates twice that for abdominal surgery in noncancer subjects are described. The case for routine thromboprophylaxis in patients receiving chemotherapy is less clear, and prospective studies investigating rates of thrombosis by tumor type, stage of disease, and chemotherapeutic regimens are required. For thromboprophylaxis in the surgical patient either low-dose heparin or low-molecular-weight (LMW) heparin are effective and safe. For patients receiving chemotherapy in advanced breast cancer, low-dose warfarin is effective. Interestingly, heparin therapy may prolong survival in patients with malignant disease; the mechanism is unclear, and observations from retrospective analysis need to be confirmed in prospective studies.
Related Links	http://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-2007-994925.pdf
Ending Page	243
Page Count	5
Starting Page	239
ISSN	00946176
e-ISSN	10989064
DOI	10.1055/s-2007-994925
Journal	Seminars in Thrombosis and Hemostasis
Issue Number	02
Volume Number	25
Language	English
Publisher	Georg Thieme Verlag KG
Publisher Date	1999-04-01
Access Restriction	Open
Subject Keyword	Journal: Seminars in Thrombosis and Hemostasis Critical Care Medicine Thrombosis Prophylaxis
Content Type	Text
Resource Type	Article
Subject	Hematology Cardiology and Cardiovascular Medicine

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