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Synthesis of Oximinotyrosine-Derived Marine Natural Products
| Content Provider | Scilit |
|---|---|
| Author | Lindel, Thomas Hentschel, Fabia |
| Copyright Year | 2009 |
| Description | This review article gives a detailed account on the synthesis of oximinotyrosine-derived marine natural products from sponges of the order Verongida. Oxidation of the amino group of the underlying bromotyrosine building block to the oxime gives rise to unique chemistry. One of the key features of the peptide-like bromotyrosine compounds is their ability to undergo cyclization to spiroisoxazolines and to form diaryl ether linkages. 1 Introduction 2 Open-Chain α-Oximinoamides 2.1 Psammaplin A 2.2 Spermatinamine, Purealidin, Verongamine 2.3 Psammaplysenes 3 Macrocyclic α-Oximinoamides 3.1 Bastadins 3.2 Bastadin Models 4 Spirocyclized α-Oximinoamides 4.1 Aerothionin 4.2 Calafianin 4.3 Purealin A 4.4 Psammaplysin 5 Aeroplysinin-1 6 Summary and Challenges |
| Related Links | http://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-0029-1218615.pdf |
| Ending Page | 204 |
| Page Count | 24 |
| Starting Page | 181 |
| ISSN | 00397881 |
| e-ISSN | 1437210X |
| DOI | 10.1055/s-0029-1218615 |
| Journal | Synthesis |
| Issue Number | 02 |
| Volume Number | 2010 |
| Language | English |
| Publisher | Georg Thieme Verlag KG |
| Publisher Date | 2009-12-16 |
| Access Restriction | Open |
| Subject Keyword | Journal: Synthesis Organic Chemistry Marine Natural Products |
| Content Type | Text |
| Resource Type | Article |
| Subject | Organic Chemistry Catalysis |