NDLI: Detection of melanoma metastases With Tc-99m-tetrofosmin

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Detection of melanoma metastases With Tc-99m-tetrofosmin

Content Provider	Scilit
Author	Koller, J. Kässmann, H. Galvan, G. Rettenbacher, L.
Copyright Year	2000
Description	Summary: Aim: The aim of this study was to evaluate Tc-99mtetrofosmin whole-body imaging in the detection of metastases in patients with malignant melanoma. Methods: In 30 patients with suspected melanoma metastases we performed whole body imaging. After administration of about 600 MBq Tc-99m-tetrofosmin dynamic images up to 10 min were performed in 7 patients (1 image per 10 sec) to evaluate the optimal tracer uptake in the metastases. In all patients whole-body images were performed 5-10 min p. i. using an acquisition time of 5 min per image. The final diagnosis was confirmed by surgical histology in 30 lesions, by computertomogaphy and clinical course in the remaining lesions. Results: Out of 64 melanoma metastases 49 were detected using Tc-99m-tetrofosmin scintigraphy (49 rp., 15 fn.). The overall sensitivity for the detection of malignant lesions was 77%. Referring only to the lymph node metastases, the sensitivity was 87% (26 rp.; 4 fn.). The maximal tracer uptake was reached 1 min after injection, with a slow decrease in the following 10 minutes. The size of the lesions ranged between 0.5 and 7.0 cm and the T/B ratios between 1.3 and 3.0 (mean 1.88). Conclusions: Tc-99m-tetrofosmin whole body imaging is a simple and side-effectless method for the detection of melanoma metastases especially of lymph node metastases. The results are comparable to Tc-99m-sestamibi and TI-201 scintigraphy.
Related Links	http://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-0038-1632253.pdf
ISSN	00295566
e-ISSN	25676407
DOI	10.1055/s-0038-1632253
Journal	Nuklearmedizin / Nuclearmedicine
Issue Number	04
Volume Number	39
Language	English
Publisher	Georg Thieme Verlag KG
Publisher Date	2000-01-01
Access Restriction	Open
Subject Keyword	Journal: Nuklearmedizin / Nuclearmedicine Schlüsselwörter Kutanes Melanom Tc-99m-tetrofosmin Szintigraphie
Content Type	Text
Resource Type	Article
Subject	Radiology, Nuclear Medicine and Imaging

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