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Association between the Degree of Twin Birthweight Discordance and Perinatal Outcomes
| Content Provider | Scilit |
|---|---|
| Author | Kim, Lena H. Caughey, Aaron B. Yee, Lynn M. Cheng, Yvonne W. |
| Copyright Year | 2018 |
| Description | Background Twin birthweight discordance is associated with adverse outcomes. Objective To determine what degree of twin birthweight discordance is associated with adverse outcomes. Study Design This is a retrospective cohort study of twins with vertex twin A delivered vaginally at 36 to 40 weeks (U.S. Vital Statistics Natality birth certificate registry data 2012–2014). The primary outcome was a composite of neonatal morbidity: 5-minute Apgar < 7, neonatal intensive care unit admission, neonatal mechanical ventilation > 6 hours, neonatal seizure, and/or neonatal transport to a higher level of care. Effect estimates were expressed as incidence rate and adjusted odds ratio (aOR) controlling for confounding using multivariate clustered analysis for between-pair effects, and multilevel random effect generalized estimating equation regressions to account for within-pair effects. We adjusted for sex discordance, breech delivery of the second twin, maternal race/ethnicity, nulliparity, age, marital status, obesity, and socioeconomic status. Results In comparison to birthweight discordance of ≤20%, aORs with 95% confidence intervals (CIs) by weight discordance of the primary outcome among 27,276 twin deliveries were as follows: 20.01 to 25% (aOR: 1.46 [95% CI: 1.29–1.65]); 25.01 to 30% (aOR: 1.96 [95% CI: 1.68–2.29]); and 30.01 to 60% (aOR: 2.97 [95% CI: 2.52–3.50]). Conclusion Twin birthweight discordance >20% was associated with increased odds of adverse neonatal outcome. |
| Related Links | http://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-0038-1675769.pdf |
| Ending Page | 974 |
| Page Count | 6 |
| Starting Page | 969 |
| ISSN | 07351631 |
| e-ISSN | 10988785 |
| DOI | 10.1055/s-0038-1675769 |
| Journal | American Journal of Perinatology |
| Issue Number | 09 |
| Volume Number | 36 |
| Language | English |
| Publisher | Georg Thieme Verlag KG |
| Publisher Date | 2018-11-26 |
| Access Restriction | Open |
| Subject Keyword | Journal: American Journal of Perinatology Obstetrics and Gynecology Twin Pregnancy Maternal Outcomes Neonatal Outcomes |
| Content Type | Text |
| Resource Type | Article |
| Subject | Pediatrics, Perinatology and Child Health Obstetrics and Gynecology |
